History¶
Making selections or adding comments in the classification pane will also save a record in the History panel on both the variant grid and variant details pages to provide a record of the selections made. This will include the name of the person who made the selection, the date, the time, the information type recorded (e.g. Transcript, or Classification), and the input provided. This input could be a drop-down selection, comment added, or selection of the Exclude variant box. If a comment is entered but the cancel button is clicked, the comment will not be saved in the history.
Editing comments¶
History items are immutable and cannot be edited or deleted. However, users can edit or remove comments from the variant comment selection if they origianlly added those comments. This can be done by opening the menu next to the comment and selecting Edit or Remove. Comments added by other users cannot be edited or removed.
When a comment is edited, the original history item is retained unchanged, and a new history item is created to record the updated comment. The edited comment becomes the most recent comment of that type, with the username and timestamp reflecting the user who made the edit and when it was made. This ensures a complete audit trail of comment changes.
If PID is entered into the system, a Service Desk ticket will need to be created to request its removal.
Updating selections¶
Existing selections can be updated using the respective drop-down menu. This will record the updated selection at the top of the history card, and retain any prior selections in the variant history for audit trail purposes.
Abbreviations
| Abbreviation | Definition |
|---|---|
| ACGS | Association for Clinical Genomic Science |
| ACMG | American College of Medical Genetics and Genomics |
| CDS | Coding DNA Sequence |
| CIP-API | Genomics England Clinical Interpretation API |
| CNV | Copy Number Variant |
| CVA | Clinical Variant Ark |
| EQ | Exit Questionnaire |
| RDDSS | Rare Disease Decision Support System |
| GEL | Genomics England |
| GMS | Genomic Medicine Service |
| GLH | Genomic Laboratory Hub |
| HGVS | Human Genome Variation Society |
| HTML | Hyper Text Markup Language |
| HSCN | Health and Social Care Network (N3) |
| IGV | Integrative Genomics Viewer |
| IB | Interpretation Browser |
| IP | Interpretation Portal |
| NGIS | National Genomics Informatics System |
| PID | Patient Identifiable Data |
| QC | Quality Control |
| SoF | Summary of Findings |
| SO | Sequence Ontology |
| SNV | Single Nucleotide Variant |
| SV | Structural Variant |
| TOMS | Test Order Management System |
| UAT | User Acceptance Testing |
| VCF | Variant Call Format File |
| VILs | Variant Interpretation Logs |
| WGS | Whole Genome Sequencing |